MERIDIA
Using directions
Make a point of keeping follow-up appointments with
your doctor. Meridia can increase your blood pressure, so it's important
to have your blood pressure and pulse monitoredat the beginning of therapy
and regularly thereafter.
Meridia can be taken with or without food. --If you
miss a dose... Take it as soon as you remember. If it is almost time
for your next dose, skip the one you missed and go back to your regular
schedule. Do not take 2 doses at once.
Store at room temperature away from heat and moisture
in a tight, light-resistantcontainer
If Meridia gives you an allergic reaction, you won't
be able to use it. You should also avoid Meridia (and certainly don''t
need it) if you suffer from the compulsive dieting disorder known as
anorexia nervosa. Do not combine Meridia with other drugs used to suppress
appetite, and do not use it within 2 weeks of taking a drug classified
as an MAO inhibitor, including the antidepressant medications Marplan,
Nardil, and Parnate
Cautions
Use Meridia with caution if you have uncontrolled high
blood pressure; it could make the problem worse. Avoid Meridia completely
if you've had a stroke or suffer from heartdisease, heart failure, or
irregular heartbeat. Also avoid it if you have severe kidney orliver
problems; the drug has not been tested under these conditions.Seizures
are a rare, but possible, side effect. If you've had seizures in the
past, use Meridia with caution. If you have a seizure while taking the
drug, stop using it and call your doctor immediately.
Any drug that acts on the nervous system can theoretically
impair judgment, thinking, and motor skills. Meridia does not seem to
have this effect, but caution is still in order until you know how the
drug affects you. If you have narrow-angle glaucoma or thyroid problems,
make sure the doctor knows;Meridia should be used with caution in these
circumstances.
If you are prone to gallstones, be aware that weight
loss can cause more of them to form.Meridia has not been tested in people
under 16 years old. It should be used with caution in those over 65.
Although it has been classified as a controlled substance (potentiallysubject
to abuse), the possibility of developing physical or psychological dependence
is low.
Possible side effects
Side effects cannot be anticipated. If any develop or
change in intensity, inform yourdoctor as soon as possible. Only your
doctor can determine if it is safe for you to continue taking Meridia.
More common side effects
may include: Abdominal pain, acid indigestion, anxiety, back pain, constipation,
cough increase, depression, dizziness, dry mouth, flu symptoms, headache,
increased appetite, insomnia, joint pain, loss of appetite, loss of
strength, nasal inflammation, nausea, nervousness, painful menstruation,
rash, sinus inflammation, stomachache, sore throat
Less common side effects
may include: Acne, abnormal thinking, agitation, allergic reaction,
arthritis, bronchitis, changes in taste, chest pain, dental problems,
diarrhea, difficulty breathing, drowsiness, ear pain, ear problems,
emotional changes, fever,gas, heavy uterine bleeding, herpes simplex
virus, increased heart rate, increased blood pressure, itching, laryngitis,
leg cramps, menstrual problems, migraine headache, muscle ache, neck
pain, rectal problems, reduced vision, stimulation, stomach and intestinal
inflammation, sweating, swelling, thirst, throbbing heartbeat, tingling
skin sensation, urinary tract infection, vaginal yeast infection, vomiting
Rare side effects may include:
Bleeding problems, kidney problems, seizures
The use of Meridia during pregnancy is not recommended.
If you are in your child-bearing years, take reliable contraceptive
measures while using this drug. If you do become pregnant, or plan on
becoming pregnant, tell your doctor immediately. It is not known whether
Meridia appears in breast milk; its use while breastfeeding is not recommended
Possible food and drug interactions
Remember that Meridia must never be taken within 2 weeks
of using an MAO inhibitorsuch as Marplan, Nardil, or Parnate. The combination
could lead to serious, even fatal, overstimulation. Meridia may also
interact with a wide variety of other prescription and over-the-counter
drugs, especially weight-reducing agents, decongestants, antidepressants,
allergy medications, and cough suppressants that contain ephedrine,
phenylpropanolamine, orpseudoephedrine. Among the many drugs that pose
a potential problem are the following:
Alcohol (excessive amounts) Dextromethorphan (found in many over-the-counter cough preparations)
Dihydroergotamine (D.H.E. Injection, Migranal Nasal Spray) Erythromycin (Eryc, Ery-Tab, PCE)
Fentanyl (Duragesic) Fluoxetine (Prozac) Fluvoxamine (Luvox)
Ketoconazole (Nizoral) Lithium (Lithobid, Lithonate)
Meperidine (Demerol)
Naratriptan (Amerge)
Paroxetine (Paxil)
Pentazocine (Talwin NX, Talacen)
Sertraline (Zoloft)
Stimulants such as amphetamines, Dexedrine, Desoxyn, Adderall, Didrex, and Ionamin
Sumatriptan (Imitrex)
Tryptophan (L-Tryptophan, Trofan)
Venlafaxine (Effexor) Zolmitriptan (Zomig)
If you have any doubt about the safety of a combination, be sure to check with your doctor.
Dosage instructions
For adults the starting dose is 10 milligrams once daily.
If you have not lost at least 4 pounds after 4 weeks, the doctor may
increase the dose to 15 milligrams daily. This is the maximum; ifweight
loss still fails to appear, Meridia will be discontinued.
For those who experience side effects at the 10-milligram
level, a 5-milligram dose may prove sufficient.
Use of Meridia for longer than 1 year has not been studied.
Although doctors have had little experience with overdoses
of Meridia, increased heart rate and blood pressure are possible results.
Since any medication taken in excess can have serious consequences,
seek medical attention immediately if you suspect an overdose.
Meridia is a registered trademark of Knoll Pharmaceutical Company |